Sweet Crosstalk

About us

Sweet Crosstalk is a multidisciplinary European Training Network (grant agreement No 814102) built to address the challenge of understanding, at a molecular level, how glycans are involved at the human mucosa–microbiota interface, and how this correlates with human well-being. Research into the human microbiome has reshaped the paradigm of our health and disease. In order to advance further, the time has arrived to understand it at a molecular level. Glycans dominate the microbiota-host interface and are thus ideally positioned to modulate these complex interactions. The research strategy of the Sweet Crosstalk programme focuses on optimal synergy between chemistry and biology. Smart chemistry drives the research to get a molecular-level grip on the role of these glycocodes and their interacting proteins, and advances in biology directs the research. The high quality and credibility of our consortium is ensured by a strong private-public partnership with complementary expertise ranging from chemical synthesis, biochemistry, structural biology to microbiology and cell biology. Our 7 academic groups are all renowned leaders in the glycoscience and microbiome fields, whereas the complementary 4 companies are specialized in glycan-based diagnostics and prophylactic therapies. This unique combination of scientific excellence and industry know-how covers the entire process from obtaining fundamental insight to the development of innovative early diagnostics and glycotherapeutics. Sweet Crosstalk also represents a unique research platform that will train 15 outstanding Early Stage Researchers to be the new generation of innovative scientists with expert knowledge and skills in interdisciplinary glycoscience and human microbiome research. Our international, intersectoral and interdisciplinary training programme will equip them with the necessary scientific and transferable skills that will make them highly competitive for both top European research institutions and the healthcare/biotech job market.

Dr. Tom Wennekes
the Netherlands
Utrecht University
  1. Chemical Biology
  2. Synthetic Organic Chemistry
  3. Carbohydrate Chemistry

Supervisor of Projects: ESR1 & ESR8

Prof. Nathalie Juge
United Kingdom
Quadram Institute
  1. Glycobiology of host-microbe interactions
  2. Biochemistry
  3. Analytical Chemistry

Supervisor of Projects: ESR2 & ESR3

Prof. Hermen Overkleeft
the Netherlands
Leiden University
  1. Chemical Biology
  2. Bio-organic Chemistry
  3. Carbohydrate Chemistry

Supervisor of Project: ESR4

Prof. Antonio Molinaro
University of Naples Federico II
  1. Organic Chemistry
  2. Oligosaccharides NMR
  3. Protein NMR

Supervisor of Projects: ESR5 & ESR6

Dr. Anne Salonen
University of Helsinki
  1. Microbiology
  2. Human Microbiome
  3. Human Milk Oligosaccharides

Supervisor of Projects: ESR7 & ESR10

Prof. Carme Rovira
University of Barcelona
  1. Computational Chemistry
  2. Computation Biology
  3. Enzyme mechanism studies

Supervisor of Project: ESR9

Prof. Patrice Cani
University of Louvain (UCL)
  1. Gut Microbiota & Human Physiology
  2. Nutrition
  3. Metabolic Diseases

Supervisor of Project: ESR11

Dr. Joeri Beauprez
Inbiose & Ghent University
  1. Complex Carbohydrates
  2. Enzymology - CAZy
  3. Cell Factories

Supervisor of Project: ESR12

Dr. Louise Vigsnæs
Glycom & Technical University Denmark
  1. Human Milk Oligosaccharides
  2. Glycobiology

Supervisor of Project: ESR13

Dr. Annick Mercenier
the Netherlands
Nutrileads & Utrecht University
  1. Dietary Fibres
  2. Structural Analysis
  3. Nutrition
  4. Gut Microbiota

Supervisor of Project: ESR14

Prof. Rob FIeld
United Kingdom
Iceni Diagnostics & University East Anglia
  1. Carbohydrate Chemistry
  2. Analytical Chemistry
  3. Point of care diagnostics

Supervisor of Project: ESR15

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